AirHint found the following cheapest return flights from Medellin (EOH) to Madrid (MAD) in September 2025 (see full year).

Return flights

08 Sep - 18 Sep	Clic Air
14 Sep - 19 Sep	Clic Air
29 Sep - 15 Oct	Clic Air
27 Sep - 18 Oct	Clic Air
15 Sep - 22 Sep	Satena
15 Sep - 25 Sep	Satena
04 Sep - 08 Sep	Clic Air
18 Sep - 05 Oct	Satena
12 Sep - 28 Sep	Clic Air
10 Sep - 17 Sep	Clic Air
07 Sep - 13 Sep	Clic Air
08 Sep - 16 Sep	Clic Air
10 Sep - 18 Sep	Satena
16 Sep - 11 Oct	Clic Air
18 Sep - 16 Oct	Satena

Also check the deals for one-way flights from Medellin to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Medellin to Madrid in September from $1144

Return flights