AirHint found the following cheapest return flights from Rome (FCO) to Cape Town (CPT) in September 2025 (see full year).

Return flights

20 Sep - 03 Oct	KLM
22 Sep - 06 Oct	Ethiopian Airlines
29 Sep - 07 Oct	Condor
27 Sep - 05 Oct	Wizz Air Malta
22 Sep - 29 Sep	KLM
28 Sep - 04 Oct	Wizz Air Malta
28 Sep - 01 Oct	Wizz Air Malta
26 Sep - 29 Sep	Ryanair
30 Sep - 04 Oct	Wizz Air Malta

Also check the deals for one-way flights from Rome to Cape Town in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Cape Town in September from $757

Return flights