AirHint found the following cheapest return flights from Rome (FCO) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

16 Oct - 25 Oct	TAP
17 Oct - 25 Oct	TAP
16 Oct - 29 Oct	TAP
01 Oct - 19 Oct	TAP
01 Oct - 31 Oct	TAP
10 Oct - 19 Oct	TAP
30 Oct - 16 Nov	TAP
12 Oct - 09 Nov	TAP
13 Oct - 20 Oct	TAP
08 Oct - 14 Oct	TAP
18 Oct - 01 Nov	TAP
18 Oct - 02 Nov	TAP
09 Oct - 16 Oct	TAP
23 Oct - 12 Nov	Iberia
30 Oct - 27 Nov	Air Europa
31 Oct - 22 Nov	Air Europa
31 Oct - 23 Nov	Air Europa
30 Oct - 23 Nov	Air Europa
30 Oct - 22 Nov	Air Europa
22 Oct - 28 Oct	Air Europa

Also check the deals for one-way flights from Rome to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in October from $615

Return flights