AirHint found the following cheapest return flights from Rome (FCO) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

03 Dec - 08 Dec	TAP
05 Dec - 08 Dec	ITA Airways	direct
05 Dec - 09 Dec	LATAM Airlines Group	direct
03 Dec - 09 Dec	LATAM Airlines Group	direct
03 Dec - 08 Dec	LATAM Airlines Group	direct
01 Dec - 09 Dec	TAP
04 Dec - 09 Dec	TAP
01 Dec - 08 Dec	TAP
03 Dec - 10 Dec	LATAM Airlines Group
03 Dec - 30 Jan	ITA Airways	direct
03 Dec - 26 Jan	LATAM Airlines Group	direct
03 Dec - 28 Jan	LATAM Airlines Group	direct
25 Dec - 30 Jan	Delta
25 Dec - 22 Jan	Delta
25 Dec - 27 Jan	Delta
25 Dec - 29 Jan	Delta
25 Dec - 31 Jan	Delta
25 Dec - 26 Jan	Delta
04 Dec - 29 Jan	Delta
10 Dec - 17 Dec	Lufthansa

Also check the deals for one-way flights from Rome to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in December from $706

Return flights