Cheapest return flights from Rome to Istanbul in April from $273

AirHint found the following cheapest return flights from Rome (FCO) to Istanbul (IST) in April 2026 (see full year).

Return flights

30 Apr - 03 May Turkish Airlines direct
01 Apr - 08 Apr Air France
19 Apr - 26 Apr Turkish Airlines direct
01 Apr - 08 Apr Turkish Airlines direct
01 Apr - 06 Apr Turkish Airlines direct
04 Apr - 07 Apr Turkish Airlines direct
30 Apr - 04 May Turkish Airlines direct
06 Apr - 08 Apr Turkish Airlines direct
25 Apr - 03 May Turkish Airlines direct
16 Apr - 19 Apr Wizz Air Malta
29 Apr - 03 May Turkish Airlines direct
09 Apr - 12 Apr Turkish Airlines direct

Also check the deals for one-way flights from Rome to Istanbul in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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