AirHint found the following cheapest return flights from Frankfurt (FRA) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

12 Sep - 20 Sep	TAP
11 Sep - 20 Sep	TAP
15 Sep - 20 Sep	TAP
12 Sep - 21 Oct	TAP
10 Sep - 17 Sep	ITA Airways
20 Sep - 20 Oct	Wizz Air Malta
08 Sep - 15 Sep	ITA Airways
12 Sep - 21 Sep	LATAM Airlines Group	direct
12 Sep - 21 Oct	LATAM Airlines Group	direct
16 Sep - 22 Sep	Delta
19 Sep - 26 Sep	Delta
17 Sep - 24 Sep	Delta
18 Sep - 25 Sep	Delta
30 Sep - 08 Oct	Delta
23 Sep - 07 Oct	Delta
23 Sep - 10 Oct	Delta
25 Sep - 06 Oct	Delta
25 Sep - 09 Oct	easyJet
20 Sep - 20 Oct	LATAM Airlines Group	direct
25 Sep - 09 Oct	LATAM Airlines Group	direct

Also check the deals for one-way flights from Frankfurt to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Sao Paulo in September from $788

Return flights