AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in October 2025 (see full year).

Return flights

28 Oct - 18 Nov	United
26 Oct - 17 Nov	Air Europa
23 Oct - 08 Nov	Air Europa
01 Oct - 13 Oct	Condor	direct
27 Oct - 09 Nov	Air Europa
27 Oct - 17 Nov	Air Europa
31 Oct - 07 Nov	Air Europa
08 Oct - 20 Oct	Condor	direct
08 Oct - 16 Oct	Condor	direct
01 Oct - 16 Oct	Condor	direct
01 Oct - 09 Oct	Condor	direct
05 Oct - 16 Oct	Condor	direct
30 Oct - 15 Nov	Air Europa
30 Oct - 14 Nov	Air Europa
30 Oct - 16 Nov	Air Europa
12 Oct - 03 Nov	Condor	direct
12 Oct - 27 Oct	Condor	direct
12 Oct - 23 Oct	Condor	direct
15 Oct - 20 Oct	Condor	direct
10 Oct - 21 Oct	Air Europa

Also check the deals for one-way flights from Frankfurt to Panama City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Panama City in October from $630

Return flights