AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in November 2025 (see full year).

Return flights

02 Nov - 15 Nov	United
02 Nov - 14 Nov	United
03 Nov - 20 Nov	United
02 Nov - 13 Nov	United
06 Nov - 17 Nov	United
10 Nov - 24 Nov	United
13 Nov - 27 Nov	United
13 Nov - 28 Nov	United
03 Nov - 10 Nov	United
18 Nov - 27 Nov	United
13 Nov - 04 Dec	United
17 Nov - 08 Dec	United
18 Nov - 09 Dec	United
20 Nov - 08 Dec	United
17 Nov - 01 Dec	United
27 Nov - 01 Dec	United
17 Nov - 08 Dec	Condor	direct
20 Nov - 08 Dec	Condor	direct
17 Nov - 01 Dec	Condor	direct
27 Nov - 01 Dec	Condor	direct

Also check the deals for one-way flights from Frankfurt to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Panama City in November from $629

Return flights