AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in December 2025 (see full year).

Return flights

11 Dec - 25 Dec	United
04 Dec - 15 Dec	Condor	direct
01 Dec - 15 Dec	Condor	direct
01 Dec - 22 Dec	Condor	direct
29 Dec - 26 Jan	United
29 Dec - 13 Jan	United
29 Dec - 08 Jan	United
05 Dec - 22 Dec	Air France
01 Dec - 14 Dec	Condor
25 Dec - 08 Jan	United
26 Dec - 09 Jan	United
11 Dec - 21 Dec	United
12 Dec - 21 Dec	United
24 Dec - 09 Jan	United
24 Dec - 10 Jan	United
26 Dec - 10 Jan	United
13 Dec - 20 Dec	Turkish Airlines
25 Dec - 10 Jan	United
11 Dec - 25 Dec	Condor	direct
25 Dec - 12 Jan	Condor	direct

Also check the deals for one-way flights from Frankfurt to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Panama City in December from $630

Return flights