AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in September 2025 (see full year).

Return flights

07 Sep - 18 Sep	Condor	direct
07 Sep - 22 Sep	Condor	direct
07 Sep - 29 Sep	Condor	direct
07 Sep - 06 Oct	Condor	direct
03 Sep - 22 Sep	Condor	direct
03 Sep - 29 Sep	Condor	direct
10 Sep - 18 Sep	Condor	direct
07 Sep - 15 Sep	Condor	direct
03 Sep - 18 Sep	Condor	direct
14 Sep - 24 Sep	United
14 Sep - 22 Sep	United
17 Sep - 02 Oct	Condor	direct
14 Sep - 02 Oct	Condor	direct
17 Sep - 06 Oct	Air Europa
19 Sep - 05 Oct	Air Europa
17 Sep - 06 Oct	Condor	direct
13 Sep - 11 Oct	KLM
28 Sep - 09 Oct	Condor	direct
25 Sep - 04 Oct	Air Europa
27 Sep - 12 Oct	Air Europa

Also check the deals for one-way flights from Frankfurt to Panama City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Panama City in September from $574

Return flights