AirHint found the following cheapest return flights from Frankfurt (FRA) to Santiago (SCL) in December 2025 (see full year).

Return flights

16 Dec - 14 Jan	Air Canada
03 Dec - 10 Dec	Air Canada
29 Dec - 22 Jan	Delta
05 Dec - 14 Jan	Air Canada
16 Dec - 23 Dec	Air Canada
01 Dec - 31 Dec	Air Canada
17 Dec - 24 Dec	Air Canada
08 Dec - 15 Jan	Delta
29 Dec - 14 Jan	Delta
04 Dec - 14 Jan	Delta
31 Dec - 21 Jan	LATAM Airlines Group
01 Dec - 28 Dec	Delta
06 Dec - 14 Jan	Iberia
31 Dec - 23 Jan	LATAM Airlines Group
22 Dec - 12 Jan	Air Canada
18 Dec - 25 Dec	Air Canada
06 Dec - 24 Dec	Iberia
12 Dec - 27 Dec	Iberia
01 Dec - 13 Dec	Delta
13 Dec - 27 Dec	Iberia

Also check the deals for one-way flights from Frankfurt to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Santiago in December from $859

Return flights