AirHint found the following cheapest return flights from Frankfurt (FRA) to Santiago (SCL) in December 2025 (see full year).

Return flights

09 Dec - 17 Dec	Iberia
07 Dec - 28 Dec	Iberia
30 Dec - 25 Jan	Iberia
05 Dec - 29 Dec	Iberia
01 Dec - 31 Jan	Air Canada
01 Dec - 31 Dec	Air Canada
06 Dec - 24 Dec	Delta
06 Dec - 26 Dec	Delta
31 Dec - 14 Jan	Delta
05 Dec - 30 Jan	Iberia
30 Dec - 22 Jan	Air Canada
06 Dec - 30 Jan	Air Canada
06 Dec - 31 Jan	Delta
09 Dec - 13 Jan	Delta
27 Dec - 19 Jan	Air Canada
24 Dec - 15 Jan	Air Canada
14 Dec - 28 Dec	Iberia
06 Dec - 11 Dec	Iberia
11 Dec - 30 Dec	Iberia
20 Dec - 30 Dec	Air Canada

Also check the deals for one-way flights from Frankfurt to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Santiago in December from $887

Return flights