AirHint found the following cheapest return flights from Frankfurt (FRA) to Santiago (SCL) in September 2025 (see full year).

Return flights

09 Sep - 23 Sep	Delta
01 Sep - 04 Oct	Delta
01 Sep - 21 Sep	Delta
06 Sep - 20 Sep	Delta
05 Sep - 28 Sep	Delta
12 Sep - 21 Sep	Delta
12 Sep - 30 Sep	Delta
01 Sep - 24 Sep	Delta
02 Sep - 09 Sep	Delta
08 Sep - 21 Sep	Delta
08 Sep - 26 Sep	Delta
15 Sep - 08 Oct	Delta
26 Sep - 18 Oct	Delta
02 Sep - 02 Oct	Delta
02 Sep - 06 Oct	Delta
26 Sep - 24 Oct	Delta
22 Sep - 03 Oct	Delta
23 Sep - 20 Oct	Delta
21 Sep - 02 Oct	Delta
21 Sep - 05 Oct	Delta

Also check the deals for one-way flights from Frankfurt to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Frankfurt to Santiago in September from $915

Return flights