AirHint found the following cheapest return flights from Guadalajara (GDL) to Panama City (PTY) in November 2025 (see full year).

Return flights

10 Nov - 18 Nov	Copa	direct
27 Nov - 06 Dec	Copa	direct
06 Nov - 10 Nov	Copa	direct
26 Nov - 01 Dec	Copa	direct
13 Nov - 19 Nov	Copa	direct
02 Nov - 07 Nov	Copa	direct
25 Nov - 28 Nov	Copa	direct
01 Nov - 08 Nov	Copa	direct
24 Nov - 28 Nov	Copa	direct
19 Nov - 24 Nov	Viva
12 Nov - 18 Nov	Copa	direct
09 Nov - 17 Nov	Viva

Also check the deals for one-way flights from Guadalajara to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guadalajara to Panama City in November from $333

Return flights