AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in October 2025 (see full year).

Return flights

20 Oct - 27 Oct	British Airways
17 Oct - 27 Oct	British Airways
20 Oct - 27 Nov	British Airways
13 Oct - 20 Oct	British Airways
12 Oct - 23 Oct	British Airways
03 Oct - 16 Oct	British Airways
01 Oct - 30 Nov	British Airways
02 Oct - 29 Nov	British Airways
24 Oct - 03 Nov	British Airways
02 Oct - 16 Oct	British Airways
28 Oct - 13 Nov	Air France
13 Oct - 24 Oct	LATAM Airlines Group
08 Oct - 22 Oct	Air France
07 Oct - 14 Oct	KLM
26 Oct - 05 Nov	Air France
08 Oct - 08 Nov	Air Europa
06 Oct - 16 Oct	KLM
01 Oct - 28 Nov	Air France
15 Oct - 15 Nov	Air France
30 Oct - 09 Nov	Lufthansa

Also check the deals for one-way flights from Sao Paulo to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in October from $846

Return flights