AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in December 2025 (see full year).

Return flights

01 Dec - 10 Dec	British Airways
01 Dec - 09 Dec	British Airways
14 Dec - 30 Dec	Air Europa
04 Dec - 26 Dec	Air France
01 Dec - 14 Dec	Air Europa
05 Dec - 15 Dec	Air France
12 Dec - 19 Dec	ITA Airways
12 Dec - 20 Dec	ITA Airways
17 Dec - 26 Dec	Air Europa
29 Dec - 29 Jan	ITA Airways
01 Dec - 15 Dec	ITA Airways
19 Dec - 04 Jan	Royal Air Maroc
28 Dec - 08 Jan	ITA Airways
19 Dec - 04 Jan	Turkish Airlines	direct
30 Dec - 06 Jan	Air Europa
22 Dec - 02 Jan	ITA Airways
29 Dec - 29 Jan	Turkish Airlines	direct
25 Dec - 02 Jan	Turkish Airlines	direct
26 Dec - 01 Jan	Turkish Airlines	direct
26 Dec - 05 Jan	Turkish Airlines	direct

Also check the deals for one-way flights from Sao Paulo to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in December from $846

Return flights