AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in September 2025 (see full year).

Return flights

30 Sep - 08 Oct	Air France
28 Sep - 07 Oct	KLM
30 Sep - 07 Oct	KLM
28 Sep - 05 Oct	KLM
02 Sep - 09 Sep	British Airways
04 Sep - 11 Sep	British Airways
16 Sep - 30 Sep	KLM
18 Sep - 30 Sep	KLM
27 Sep - 07 Oct	KLM
30 Sep - 13 Oct	Air France
21 Sep - 03 Oct	Air France
30 Sep - 31 Oct	Air France
16 Sep - 29 Sep	KLM
18 Sep - 29 Sep	KLM
26 Sep - 09 Oct	Air France
25 Sep - 02 Oct	Air Europa
15 Sep - 25 Sep	British Airways
10 Sep - 18 Sep	British Airways
07 Sep - 19 Sep	Air France
03 Sep - 10 Sep	British Airways

Also check the deals for one-way flights from Sao Paulo to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in September from $956

Return flights