AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in September 2025 (see full year).

Return flights

25 Sep - 08 Oct	British Airways
16 Sep - 23 Sep	British Airways
16 Sep - 08 Oct	British Airways
30 Sep - 07 Oct	GOL Linhas Aéreas
23 Sep - 09 Oct	British Airways
30 Sep - 13 Oct	British Airways
17 Sep - 29 Sep	British Airways
30 Sep - 12 Oct	British Airways
25 Sep - 07 Oct	LATAM Airlines Group
28 Sep - 04 Oct	Avianca
21 Sep - 29 Sep	British Airways
28 Sep - 05 Oct	LATAM Airlines Group
10 Sep - 17 Sep	Copa
28 Sep - 12 Oct	Air France
14 Sep - 16 Sep	Copa
08 Sep - 23 Sep	Ethiopian Airlines
04 Sep - 17 Sep	Avianca
10 Sep - 19 Sep	Copa
12 Sep - 22 Sep	Copa
07 Sep - 10 Sep	Copa

Also check the deals for one-way flights from Sao Paulo to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in September from $862

Return flights