AirHint found the following cheapest return flights from Sao Paulo (GRU) to Madrid (MAD) in December 2025 (see full year).

Return flights

16 Dec - 28 Dec	ITA Airways
16 Dec - 01 Jan	ITA Airways
16 Dec - 29 Dec	ITA Airways
16 Dec - 31 Dec	ITA Airways
16 Dec - 30 Dec	ITA Airways
16 Dec - 25 Dec	GOL Linhas Aéreas
16 Dec - 23 Dec	GOL Linhas Aéreas
16 Dec - 26 Dec	KLM
16 Dec - 27 Dec	KLM
18 Dec - 28 Dec	Iberia	direct
18 Dec - 21 Jan	Iberia	direct
18 Dec - 01 Jan	Iberia	direct
16 Dec - 15 Jan	ITA Airways
24 Dec - 31 Dec	Iberia	direct
24 Dec - 27 Jan	Iberia	direct
24 Dec - 01 Jan	Iberia	direct
24 Dec - 22 Jan	Iberia	direct
19 Dec - 01 Jan	Iberia	direct
16 Dec - 13 Jan	KLM
16 Dec - 12 Jan	KLM

Also check the deals for one-way flights from Sao Paulo to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Madrid in December from $795

Return flights