AirHint found the following cheapest return flights from Sao Paulo (GRU) to Prague (PRG) in October 2025 (see full year).

Return flights

27 Oct - 08 Nov	TAP
26 Oct - 10 Nov	TAP
17 Oct - 24 Oct	TAP
19 Oct - 04 Nov	Air France
21 Oct - 28 Oct	KLM
01 Oct - 06 Oct	Avianca
03 Oct - 05 Oct	Avianca
18 Oct - 22 Oct	LATAM Airlines Group
08 Oct - 15 Oct	Air Europa
03 Oct - 13 Oct	Air China
10 Oct - 27 Oct	Copa
11 Oct - 27 Oct	Copa
06 Oct - 20 Oct	GOL Linhas Aéreas

Also check the deals for one-way flights from Sao Paulo to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Prague in October from $851

Return flights