AirHint found the following cheapest return flights from Sao Paulo (GRU) to Panama City (PTY) in November 2025 (see full year).

Return flights

21 Nov - 24 Nov	GOL Linhas Aéreas
23 Nov - 28 Nov	GOL Linhas Aéreas
13 Nov - 20 Nov	Sky Airline
14 Nov - 18 Nov	Copa	direct
19 Nov - 24 Nov	Copa	direct
17 Nov - 27 Nov	Copa	direct
29 Nov - 06 Dec	Avianca
29 Nov - 05 Dec	Avianca
16 Nov - 21 Nov	Avianca
23 Nov - 28 Nov	Copa	direct
12 Nov - 18 Nov	Avianca
21 Nov - 24 Nov	Copa	direct
25 Nov - 08 Dec	GOL Linhas Aéreas
30 Nov - 04 Dec	GOL Linhas Aéreas
23 Nov - 01 Dec	GOL Linhas Aéreas
28 Nov - 06 Dec	GOL Linhas Aéreas
30 Nov - 04 Dec	Copa	direct
28 Nov - 05 Dec	GOL Linhas Aéreas
29 Nov - 06 Dec	Copa	direct
29 Nov - 05 Dec	Copa	direct

Also check the deals for one-way flights from Sao Paulo to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Panama City in November from $477

Return flights