AirHint found the following cheapest return flights from Sao Paulo (GRU) to Panama City (PTY) in November 2025 (see full year).

Return flights

19 Nov - 23 Nov	Avianca
22 Nov - 28 Nov	GOL Linhas Aéreas
21 Nov - 24 Nov	Avianca
21 Nov - 24 Nov	Copa	direct
19 Nov - 24 Nov	Copa	direct
18 Nov - 18 Dec	Copa	direct
20 Nov - 29 Nov	Avianca
30 Nov - 04 Dec	GOL Linhas Aéreas
16 Nov - 24 Nov	Avianca
13 Nov - 18 Nov	Sky Airline
16 Nov - 24 Nov	Copa	direct
22 Nov - 28 Nov	Copa	direct
27 Nov - 07 Dec	GOL Linhas Aéreas
30 Nov - 04 Dec	Copa	direct
29 Nov - 05 Dec	GOL Linhas Aéreas
14 Nov - 26 Dec	Copa	direct
28 Nov - 06 Dec	GOL Linhas Aéreas
28 Nov - 04 Dec	GOL Linhas Aéreas
29 Nov - 05 Dec	Copa	direct
29 Nov - 06 Dec	Copa	direct

Also check the deals for one-way flights from Sao Paulo to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Panama City in November from $480

Return flights