AirHint found the following cheapest return flights from Sao Paulo (GRU) to Panama City (PTY) in April 2026 (see full year).

Return flights

15 Apr - 26 Apr	GOL Linhas Aéreas
17 Apr - 22 Apr	GOL Linhas Aéreas
11 Apr - 18 Apr	GOL Linhas Aéreas
16 Apr - 22 Apr	GOL Linhas Aéreas
01 Apr - 15 Apr	GOL Linhas Aéreas
11 Apr - 18 Apr	Copa	direct
16 Apr - 22 Apr	Copa	direct
01 Apr - 05 Apr	Copa	direct
15 Apr - 26 Apr	Copa	direct
01 Apr - 15 Apr	Copa	direct

Also check the deals for one-way flights from Sao Paulo to Panama City in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Panama City in April from $477

Return flights