Cheapest return flights from Sao Paulo to Santiago in December from $224

AirHint found the following cheapest return flights from Sao Paulo (GRU) to Santiago (SCL) in December 2025 (see full year).

Return flights

07 Dec - 10 Dec LATAM Airlines Group
07 Dec - 21 Dec LATAM Airlines Group
04 Dec - 16 Dec Sky Airline
05 Dec - 19 Dec LATAM Airlines Group
09 Dec - 17 Dec Sky Airline
05 Dec - 16 Dec Sky Airline direct
12 Dec - 23 Dec Sky Airline direct
01 Dec - 20 Dec Sky Airline direct
14 Dec - 19 Dec Sky Airline direct
05 Dec - 10 Dec LATAM Airlines Group direct
23 Dec - 07 Jan LATAM Airlines Group
31 Dec - 08 Jan Sky Airline direct
07 Dec - 08 Jan Sky Airline direct
16 Dec - 07 Jan Sky Airline
18 Dec - 08 Jan Sky Airline direct
15 Dec - 08 Jan Sky Airline direct
16 Dec - 15 Jan Sky Airline
25 Dec - 07 Jan LATAM Airlines Group
01 Dec - 01 Jan Sky Airline direct
07 Dec - 25 Jan Sky Airline direct

Also check the deals for one-way flights from Sao Paulo to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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