AirHint found the following cheapest return flights from Guatemala City (GUA) to Madrid (MAD) in October 2025 (see full year).

Return flights

08 Oct - 20 Oct	Spirit Airlines
01 Oct - 16 Oct	Spirit Airlines
06 Oct - 15 Oct	jetBlue
04 Oct - 18 Oct	Spirit Airlines
02 Oct - 15 Oct	Spirit Airlines
14 Oct - 30 Oct	jetBlue
03 Oct - 11 Oct	Avianca
27 Oct - 11 Nov	Volaris El Salvador
31 Oct - 15 Nov	Air Canada
01 Oct - 19 Oct	Spirit Airlines
05 Oct - 18 Oct	Air Canada
13 Oct - 10 Nov	Volaris Costa Rica
26 Oct - 16 Nov	Avianca
30 Oct - 05 Nov	Aeromexico
06 Oct - 20 Oct	jetBlue
23 Oct - 16 Nov	Avianca
24 Oct - 16 Nov	Avianca
14 Oct - 14 Nov	Avianca

Also check the deals for one-way flights from Guatemala City to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guatemala City to Madrid in October from $688

Return flights