AirHint found the following cheapest return flights from Guatemala City (GUA) to Madrid (MAD) in October 2025 (see full year).

Return flights

20 Oct - 02 Nov	Avianca
09 Oct - 02 Nov	Spirit Airlines
30 Oct - 05 Nov	Spirit Airlines
09 Oct - 26 Oct	Spirit Airlines
24 Oct - 15 Nov	Avianca
19 Oct - 30 Oct	Avianca
24 Oct - 30 Oct	Avianca
01 Oct - 08 Oct	Avianca
03 Oct - 10 Oct	Spirit Airlines
12 Oct - 28 Oct	Avianca
31 Oct - 15 Nov	Air Canada
03 Oct - 23 Oct	United
01 Oct - 10 Oct	United
20 Oct - 07 Nov	United
14 Oct - 30 Oct	Avianca
17 Oct - 27 Oct	United
24 Oct - 08 Nov	United
20 Oct - 17 Nov	United
17 Oct - 01 Nov	Air Europa
29 Oct - 24 Nov	Iberia

Also check the deals for one-way flights from Guatemala City to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guatemala City to Madrid in October from $729

Return flights