Cheapest return flights from Guatemala City to Panama City in October from $309

AirHint found the following cheapest return flights from Guatemala City (GUA) to Panama City (PTY) in October 2025 (see full year).

Return flights

09 Oct - 13 Oct Avianca
14 Oct - 15 Oct Avianca
25 Oct - 29 Oct Avianca
08 Oct - 12 Oct Avianca
22 Oct - 29 Oct Avianca
19 Oct - 26 Oct Avianca
20 Oct - 26 Oct Avianca
31 Oct - 09 Nov Copa direct
25 Oct - 29 Oct Copa direct
08 Oct - 12 Oct Copa direct
19 Oct - 26 Oct Copa direct

Also check the deals for one-way flights from Guatemala City to Panama City in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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