Cheapest return flights from Guatemala City to Panama City in October from $267

AirHint found the following cheapest return flights from Guatemala City (GUA) to Panama City (PTY) in October 2025 (see full year).

Return flights

02 Oct - 06 Oct Copa
15 Oct - 18 Oct Avianca
13 Oct - 20 Oct Copa direct
06 Oct - 16 Oct Copa
13 Oct - 17 Oct Copa direct
04 Oct - 07 Oct Copa direct
06 Oct - 09 Oct Copa
15 Oct - 18 Oct Copa direct
14 Oct - 21 Oct Copa
19 Oct - 25 Oct Copa direct

Also check the deals for one-way flights from Guatemala City to Panama City in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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