Cheapest return flights from Guatemala City to Panama City in October from $248

AirHint found the following cheapest return flights from Guatemala City (GUA) to Panama City (PTY) in October 2025 (see full year).

Return flights

03 Oct - 07 Oct Copa
06 Oct - 13 Oct Copa
03 Oct - 05 Oct Copa
02 Oct - 04 Oct Copa direct
02 Oct - 05 Oct Copa direct
15 Oct - 19 Oct Copa direct
12 Oct - 21 Oct Copa direct
13 Oct - 19 Oct Copa direct
23 Oct - 27 Oct Copa direct
21 Oct - 25 Oct Copa direct
31 Oct - 02 Nov Copa direct
24 Oct - 03 Nov Copa direct
29 Oct - 05 Nov Copa direct
31 Oct - 03 Nov Copa direct
06 Oct - 03 Nov Copa direct
26 Oct - 01 Nov Copa

Also check the deals for one-way flights from Guatemala City to Panama City in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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