AirHint found the following cheapest return flights from Guatemala City (GUA) to Panama City (PTY) in November 2025 (see full year).

Return flights

13 Nov - 17 Nov	Avianca
18 Nov - 22 Nov	Avianca
13 Nov - 18 Nov	Avianca
10 Nov - 14 Nov	Avianca
24 Nov - 28 Nov	Avianca
13 Nov - 17 Nov	Copa	direct
07 Nov - 13 Nov	Copa	direct
01 Nov - 02 Nov	Copa	direct
06 Nov - 09 Nov	Copa	direct
06 Nov - 10 Nov	Copa	direct
25 Nov - 02 Dec	Avianca
28 Nov - 03 Dec	Avianca
29 Nov - 05 Dec	Copa	direct
30 Nov - 03 Dec	Copa	direct
28 Nov - 03 Dec	Copa	direct
25 Nov - 02 Dec	Copa	direct

Also check the deals for one-way flights from Guatemala City to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guatemala City to Panama City in November from $200

Return flights