Cheapest return flights from Guatemala City to Panama City in December from $179

AirHint found the following cheapest return flights from Guatemala City (GUA) to Panama City (PTY) in December 2025 (see full year).

Return flights

04 Dec - 09 Dec Avianca
15 Dec - 21 Dec Avianca
18 Dec - 23 Dec Avianca
26 Dec - 28 Dec Avianca
26 Dec - 29 Dec Avianca
26 Dec - 30 Dec Avianca
22 Dec - 28 Dec Copa direct
19 Dec - 23 Dec Copa direct
13 Dec - 22 Dec Copa direct
02 Dec - 05 Dec Copa
30 Dec - 02 Jan Copa direct

Also check the deals for one-way flights from Guatemala City to Panama City in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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