Cheapest return flights from Guatemala City to Panama City in September from $179

AirHint found the following cheapest return flights from Guatemala City (GUA) to Panama City (PTY) in September 2025 (see full year).

Return flights

19 Sep - 26 Sep Avianca
30 Sep - 02 Oct Avianca
29 Sep - 03 Oct Avianca
17 Sep - 22 Sep Avianca
30 Sep - 04 Oct Avianca
20 Sep - 27 Sep Avianca
30 Sep - 05 Oct Avianca
19 Sep - 28 Sep Avianca
28 Sep - 29 Sep Avianca
21 Sep - 22 Sep Avianca
17 Sep - 26 Sep Avianca
24 Sep - 27 Sep Copa direct
24 Sep - 28 Sep Copa direct
25 Sep - 29 Sep Copa direct
30 Sep - 02 Oct Copa direct
30 Sep - 04 Oct Copa direct
29 Sep - 03 Oct Copa direct
30 Sep - 05 Oct Copa direct
20 Sep - 04 Oct Copa

Also check the deals for one-way flights from Guatemala City to Panama City in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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