Cheapest return flights from Guatemala City to Panama City in September from $207

AirHint found the following cheapest return flights from Guatemala City (GUA) to Panama City (PTY) in September 2025 (see full year).

Return flights

25 Sep - 30 Sep Copa
20 Sep - 27 Sep Copa
24 Sep - 27 Sep Copa
23 Sep - 24 Sep Copa
28 Sep - 01 Oct Copa
29 Sep - 06 Oct Copa
20 Sep - 23 Sep Copa
30 Sep - 03 Oct Copa direct
29 Sep - 06 Oct Copa direct
26 Sep - 29 Sep Copa direct
25 Sep - 30 Sep Copa direct
25 Sep - 26 Sep Copa direct
26 Sep - 30 Sep Copa direct
30 Sep - 07 Oct Copa direct
23 Sep - 24 Sep Copa direct

Also check the deals for one-way flights from Guatemala City to Panama City in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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