AirHint found the following cheapest return flights from Guatemala City (GUA) to Santo Domingo (SDQ) in December 2025 (see full year).

Return flights

20 Dec - 30 Dec	Copa
25 Dec - 30 Dec	Copa
09 Dec - 13 Dec	Copa
15 Dec - 22 Dec	Copa
06 Dec - 11 Dec	Copa
18 Dec - 22 Dec	Copa
08 Dec - 13 Dec	Copa
20 Dec - 30 Dec	Arajet	direct
25 Dec - 30 Dec	Arajet	direct
16 Dec - 20 Dec	Copa
27 Dec - 01 Jan	Arajet	direct
27 Dec - 03 Jan	Copa
27 Dec - 03 Jan	Arajet	direct
26 Dec - 02 Jan	Copa

Also check the deals for one-way flights from Guatemala City to Santo Domingo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guatemala City to Santo Domingo in December from $263

Return flights