AirHint found the following cheapest return flights from Guatemala City (GUA) to Santo Domingo (SDQ) in December 2025 (see full year).

Return flights

23 Dec - 25 Dec	Arajet	direct
06 Dec - 09 Dec	Arajet	direct
08 Dec - 13 Dec	Copa
06 Dec - 10 Dec	Copa
22 Dec - 30 Dec	Copa
30 Dec - 12 Jan	Arajet	direct
25 Dec - 30 Dec	Copa
20 Dec - 30 Dec	Arajet	direct
25 Dec - 30 Dec	Arajet	direct
04 Dec - 11 Dec	Arajet	direct
19 Dec - 23 Dec	Copa
23 Dec - 05 Jan	Arajet	direct
18 Dec - 05 Jan	Arajet	direct
22 Dec - 03 Jan	Copa
27 Dec - 05 Jan	Arajet	direct
25 Dec - 03 Jan	Copa
29 Dec - 05 Jan	Arajet	direct
31 Dec - 03 Jan	Copa
21 Dec - 03 Jan	Copa
25 Dec - 03 Jan	Arajet	direct

Also check the deals for one-way flights from Guatemala City to Santo Domingo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santo Domingo

Cheap car rent in Santo Domingo

Cheapest return flights from Guatemala City to Santo Domingo in December from $289

Return flights