AirHint found the following cheapest return flights from Guatemala City (GUA) to Santo Domingo (SDQ) in December 2025 (see full year).

Return flights

29 Dec - 10 Jan	Arajet	direct
30 Dec - 12 Jan	Arajet	direct
23 Dec - 30 Dec	Arajet	direct
27 Dec - 30 Dec	Arajet	direct
27 Dec - 29 Dec	Arajet	direct
27 Dec - 31 Dec	Arajet
25 Dec - 30 Dec	Arajet	direct
25 Dec - 29 Dec	Arajet	direct
24 Dec - 31 Dec	Avianca
25 Dec - 01 Jan	Arajet	direct
23 Dec - 27 Dec	Arajet	direct
20 Dec - 30 Dec	Arajet	direct
22 Dec - 08 Jan	Arajet	direct
28 Dec - 11 Jan	Copa
29 Dec - 11 Jan	Copa
31 Dec - 11 Jan	Copa
28 Dec - 09 Jan	Copa
26 Dec - 30 Dec	Volaris El Salvador
25 Dec - 05 Jan	Arajet
29 Dec - 05 Jan	Arajet	direct

Also check the deals for one-way flights from Guatemala City to Santo Domingo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guatemala City to Santo Domingo in December from $366

Return flights