AirHint found the following cheapest return flights from Guayaquil (GYE) to Istanbul (IST) in December 2025 (see full year).
Return flights
| 24 Dec - 31 Dec | KLM | ||
| 04 Dec - 13 Dec | jetBlue | ||
| 23 Dec - 30 Dec | KLM | ||
| 24 Dec - 01 Jan | Air Europa | ||
| 23 Dec - 01 Jan | LATAM Airlines Group | ||
| 25 Dec - 04 Jan | LATAM Airlines Group | ||
| 23 Dec - 28 Dec | Avianca |
Also check the deals for one-way flights from Guayaquil to Istanbul in December.
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