AirHint found the following cheapest return flights from Guayaquil (GYE) to Rio Negro (MDE) in November 2025 (see full year).

Return flights

13 Nov - 19 Nov	Copa
13 Nov - 18 Nov	Copa
28 Nov - 04 Dec	Copa
14 Nov - 17 Nov	Copa
26 Nov - 28 Nov	Avianca	direct
17 Nov - 21 Nov	Avianca	direct
14 Nov - 17 Nov	Avianca	direct
21 Nov - 25 Nov	Copa
22 Nov - 25 Nov	Copa
23 Nov - 26 Nov	Avianca
21 Nov - 23 Nov	Avianca
26 Nov - 02 Dec	Avianca
28 Nov - 02 Dec	Avianca
21 Nov - 01 Dec	Avianca
27 Nov - 02 Dec	Avianca

Also check the deals for one-way flights from Guayaquil to Rio Negro in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guayaquil to Rio Negro in November from $236

Return flights