Cheapest return flights from Guayaquil to Rio Negro in September from $263

AirHint found the following cheapest return flights from Guayaquil (GYE) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

08 Sep - 26 Sep Copa
15 Sep - 26 Sep Copa
08 Sep - 12 Sep Copa
12 Sep - 26 Sep Copa
19 Sep - 21 Sep Avianca
03 Sep - 05 Sep Copa
15 Sep - 26 Sep Avianca direct
11 Sep - 25 Sep Copa
20 Sep - 26 Sep Copa
15 Sep - 19 Sep Avianca direct
30 Sep - 03 Oct Copa

Also check the deals for one-way flights from Guayaquil to Rio Negro in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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