AirHint found the following cheapest return flights from Guayaquil (GYE) to Panama City (PTY) in February 2026 (see full year).

Return flights

02 Feb - 09 Feb	Avianca
05 Feb - 08 Feb	Avianca
06 Feb - 10 Feb	Avianca
06 Feb - 09 Feb	Avianca
17 Feb - 23 Feb	Avianca
14 Feb - 20 Feb	Avianca
12 Feb - 15 Feb	Copa	direct
02 Feb - 07 Feb	Copa	direct
04 Feb - 10 Feb	Copa	direct
09 Feb - 13 Feb	Copa	direct
20 Feb - 20 Mar	Copa	direct
22 Feb - 12 Mar	Copa	direct
23 Feb - 12 Mar	Copa	direct
21 Feb - 01 Mar	Copa	direct
27 Feb - 02 Mar	Avianca
27 Feb - 15 Mar	Avianca
28 Feb - 15 Mar	Avianca
26 Feb - 11 Mar	Avianca
26 Feb - 02 Mar	Avianca
26 Feb - 03 Mar	Avianca

Also check the deals for one-way flights from Guayaquil to Panama City in February.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Cheapest return flights from Guayaquil to Panama City in February from $299

Return flights