Cheapest return flights from Guayaquil to Panama City in May from $229

Best time to book flights for Guayaquil (GYE) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Guayaquil (GYE) to Panama City (PTY) in May 2025 (see full year).

Return flights

13 May - 17 May Avianca
05 May - 08 May Avianca
07 May - 10 May Avianca
15 May - 21 May Avianca
14 May - 17 May Avianca
06 May - 15 May Avianca
24 May - 27 May Avianca
14 May - 16 May Avianca
16 May - 19 May Avianca
25 May - 28 May Avianca
30 May - 01 Jun Avianca
31 May - 03 Jun Avianca
25 May - 01 Jun Copa direct
30 May - 01 Jun Copa direct
31 May - 03 Jun Copa direct
30 May - 03 Jun Copa direct
30 May - 08 Jun Avianca
30 May - 08 Jun Copa direct

Also check the deals for one-way flights from Guayaquil to Panama City in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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