Cheapest return flights from Guayaquil to Panama City in September from $229

Best time to book flights for Guayaquil (GYE) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Guayaquil (GYE) to Panama City (PTY) in September 2025 (see full year).

Return flights

03 Sep - 22 Sep Avianca
05 Sep - 08 Sep Avianca
10 Sep - 15 Sep Avianca
03 Sep - 07 Sep Avianca
04 Sep - 11 Sep Avianca
20 Sep - 28 Sep Avianca
24 Sep - 29 Sep Avianca
04 Sep - 09 Sep Avianca
11 Sep - 15 Sep Copa direct
20 Sep - 28 Sep Copa direct

Also check the deals for one-way flights from Guayaquil to Panama City in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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