Cheapest return flights from Guayaquil to Santiago in October from $409

AirHint found the following cheapest return flights from Guayaquil (GYE) to Santiago (SCL) in October 2025 (see full year).

Return flights

09 Oct - 12 Oct Avianca
09 Oct - 18 Oct Avianca
02 Oct - 09 Oct Avianca
22 Oct - 29 Oct Avianca
19 Oct - 29 Oct Avianca
14 Oct - 28 Oct Avianca
22 Oct - 30 Oct Avianca
07 Oct - 24 Oct Avianca
02 Oct - 09 Oct LATAM Airlines Group direct
26 Oct - 07 Nov LATAM Airlines Group
27 Oct - 03 Nov LATAM Airlines Group
04 Oct - 31 Oct Avianca
31 Oct - 15 Nov LATAM Airlines Group

Also check the deals for one-way flights from Guayaquil to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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