AirHint found the following cheapest return flights from Guayaquil (GYE) to Santiago (SCL) in November 2025 (see full year).

Return flights

11 Nov - 22 Nov	Avianca
18 Nov - 22 Nov	Avianca
16 Nov - 22 Nov	Avianca
16 Nov - 24 Nov	Avianca
04 Nov - 12 Nov	Avianca
18 Nov - 21 Nov	LATAM Airlines Group
14 Nov - 21 Nov	Avianca
20 Nov - 02 Dec	LATAM Airlines Group
11 Nov - 11 Dec	LATAM Airlines Group
24 Nov - 02 Dec	LATAM Airlines Group
17 Nov - 23 Nov	Avianca
22 Nov - 30 Nov	Avianca
27 Nov - 30 Nov	Avianca
27 Nov - 05 Dec	Avianca
13 Nov - 21 Dec	Avianca
16 Nov - 19 Dec	Avianca
28 Nov - 26 Dec	LATAM Airlines Group
17 Nov - 21 Dec	Avianca

Also check the deals for one-way flights from Guayaquil to Santiago in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guayaquil to Santiago in November from $323

Return flights