AirHint found the following cheapest return flights from Houston (HOU) to Rome (FCO) in October 2025 (see full year).

Return flights

27 Oct - 08 Nov	Spirit Airlines
23 Oct - 15 Nov	Frontier Airlines
20 Oct - 05 Nov	United
19 Oct - 04 Nov	United
08 Oct - 14 Oct	Spirit Airlines
01 Oct - 08 Oct	Spirit Airlines
08 Oct - 13 Oct	Spirit Airlines
03 Oct - 07 Oct	Spirit Airlines
05 Oct - 25 Oct	Spirit Airlines
10 Oct - 01 Nov	Spirit Airlines
01 Oct - 13 Oct	Spirit Airlines
18 Oct - 25 Oct	Spirit Airlines
16 Oct - 26 Oct	Frontier Airlines
17 Oct - 25 Oct	Frontier Airlines
02 Oct - 27 Oct	Spirit Airlines

Also check the deals for one-way flights from Houston to Rome in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Rome in October from $539

Return flights