AirHint found the following cheapest return flights from Houston (HOU) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

23 Oct - 31 Oct	Spirit Airlines
09 Oct - 23 Oct	United	direct
15 Oct - 29 Oct	United	direct
16 Oct - 30 Oct	United	direct
01 Oct - 15 Oct	United
02 Oct - 16 Oct	United
06 Oct - 20 Oct	United
07 Oct - 21 Oct	United
13 Oct - 27 Oct	United
20 Oct - 03 Nov	United	direct
23 Oct - 06 Nov	United	direct
21 Oct - 04 Nov	United
22 Oct - 05 Nov	United
27 Oct - 10 Nov	United
28 Oct - 11 Nov	United
29 Oct - 12 Nov	United
08 Oct - 22 Oct	United	direct
18 Oct - 01 Nov	United	direct
19 Oct - 02 Nov	United	direct
24 Oct - 07 Nov	United	direct

Also check the deals for one-way flights from Houston to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Sao Paulo

Cheap car rent in Sao Paulo

Cheapest return flights from Houston to Sao Paulo in October from $502

Return flights