AirHint found the following cheapest return flights from Houston (HOU) to Guatemala City (GUA) in May 2026 (see full year).

Return flights

16 May - 29 May	Avianca
04 May - 09 May	Avianca
20 May - 27 May	Avianca
12 May - 19 May	Avianca
07 May - 12 May	Avianca
30 May - 02 Jun	Avianca
04 May - 08 May	Avianca
06 May - 11 May	Avianca
20 May - 25 May	Avianca
09 May - 11 May	Avianca
06 May - 10 May	Avianca
30 May - 08 Jun	Avianca
20 May - 02 Jun	Spirit Airlines
26 May - 02 Jun	Spirit Airlines
18 May - 02 Jun	Spirit Airlines
28 May - 02 Jun	Spirit Airlines
17 May - 02 Jun	Spirit Airlines
14 May - 02 Jun	Spirit Airlines
28 May - 08 Jun	Avianca
12 May - 02 Jun	Spirit Airlines

Also check the deals for one-way flights from Houston to Guatemala City in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Guatemala City in May from $210

Return flights