AirHint found the following cheapest return flights from Houston (HOU) to Rio Negro (MDE) in November 2025 (see full year).

Return flights

01 Nov - 03 Nov	Spirit Airlines
01 Nov - 10 Nov	Spirit Airlines
04 Nov - 10 Nov	Spirit Airlines
02 Nov - 03 Nov	Spirit Airlines
01 Nov - 02 Nov	Spirit Airlines
02 Nov - 10 Nov	Spirit Airlines
01 Nov - 09 Nov	Spirit Airlines
04 Nov - 09 Nov	Spirit Airlines
07 Nov - 09 Nov	Spirit Airlines
02 Nov - 09 Nov	Spirit Airlines
20 Nov - 09 Dec	Spirit Airlines
20 Nov - 10 Dec	Spirit Airlines
12 Nov - 01 Dec	Spirit Airlines
20 Nov - 01 Dec	Viva
20 Nov - 01 Dec	United	direct

Also check the deals for one-way flights from Houston to Rio Negro in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rio Negro

Cheap car rent in Rio Negro

Cheapest return flights from Houston to Rio Negro in November from $287

Return flights