Cheapest return flights from Houston to Rio Negro in April from $304

AirHint found the following cheapest return flights from Houston (HOU) to Rio Negro (MDE) in April 2026 (see full year).

Return flights

14 Apr - 19 Apr Spirit Airlines
11 Apr - 18 Apr Spirit Airlines
09 Apr - 19 Apr Spirit Airlines
21 Apr - 26 Apr Spirit Airlines
02 Apr - 18 Apr Spirit Airlines
14 Apr - 18 Apr Spirit Airlines
01 Apr - 18 Apr Spirit Airlines
15 Apr - 18 Apr Spirit Airlines
26 Apr - 27 Apr Spirit Airlines
17 Apr - 06 May Frontier Airlines
08 Apr - 10 Apr Spirit Airlines
26 Apr - 14 May Spirit Airlines
26 Apr - 06 May Spirit Airlines
21 Apr - 06 May Spirit Airlines
23 Apr - 14 May Spirit Airlines
18 Apr - 06 May Spirit Airlines
23 Apr - 06 May Spirit Airlines
19 Apr - 06 May Spirit Airlines
20 Apr - 06 May Spirit Airlines
24 Apr - 14 May Spirit Airlines

Also check the deals for one-way flights from Houston to Rio Negro in April.

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