Cheapest return flights from Houston to Panama City in December from $574

AirHint found the following cheapest return flights from Houston (HOU) to Panama City (PTY) in December 2025 (see full year).

Return flights

17 Dec - 22 Dec Spirit Airlines
31 Dec - 05 Jan Spirit Airlines
16 Dec - 21 Dec Spirit Airlines
21 Dec - 27 Dec Frontier Airlines
23 Dec - 05 Jan Frontier Airlines
21 Dec - 28 Dec Frontier Airlines
29 Dec - 02 Jan Spirit Airlines
27 Dec - 03 Jan Spirit Airlines
17 Dec - 22 Dec United direct
16 Dec - 21 Dec United direct
21 Dec - 28 Dec United direct
27 Dec - 03 Jan United direct
23 Dec - 05 Jan United direct
31 Dec - 05 Jan United direct
21 Dec - 27 Dec United direct
29 Dec - 02 Jan United direct

Also check the deals for one-way flights from Houston to Panama City in December.

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