AirHint found the following cheapest return flights from Houston (HOU) to Panama City (PTY) in March 2026 (see full year).

Return flights

03 Mar - 06 Mar	Spirit Airlines
03 Mar - 07 Mar	Spirit Airlines
29 Mar - 01 Apr	Avianca
08 Mar - 15 Mar	Frontier Airlines
20 Mar - 30 Mar	Spirit Airlines
30 Mar - 05 Apr	Spirit Airlines
07 Mar - 14 Mar	Frontier Airlines
25 Mar - 01 Apr	United	direct
20 Mar - 30 Mar	United	direct
07 Mar - 14 Mar	United	direct
06 Mar - 14 Mar	United	direct
08 Mar - 15 Mar	United	direct
30 Mar - 05 Apr	United	direct
29 Mar - 01 Apr	United	direct
03 Mar - 06 Mar	United	direct

Also check the deals for one-way flights from Houston to Panama City in March.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Panama City in March from $488

Return flights