Cheapest return flights from Houston to Panama City in April from $476

AirHint found the following cheapest return flights from Houston (HOU) to Panama City (PTY) in April 2026 (see full year).

Return flights

10 Apr - 17 Apr Frontier Airlines
09 Apr - 12 Apr Spirit Airlines
02 Apr - 06 Apr Frontier Airlines
28 Apr - 03 May Spirit Airlines
01 Apr - 05 Apr Spirit Airlines
03 Apr - 12 Apr Spirit Airlines
03 Apr - 12 Apr Copa direct
10 Apr - 17 Apr Copa direct
09 Apr - 12 Apr Copa direct
01 Apr - 05 Apr Copa direct
28 Apr - 03 May Copa direct
02 Apr - 06 Apr United direct
30 Apr - 05 May United direct

Also check the deals for one-way flights from Houston to Panama City in April.

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