AirHint found the following cheapest return flights from Houston (HOU) to Panama City (PTY) in July 2025 (see full year).

Return flights

06 Jul - 10 Jul	Spirit Airlines
26 Jul - 02 Aug	Spirit Airlines
17 Jul - 20 Jul	Spirit Airlines
05 Jul - 09 Jul	Spirit Airlines
03 Jul - 13 Jul	Frontier Airlines
03 Jul - 04 Aug	Frontier Airlines
02 Jul - 08 Jul	Avianca
24 Jul - 28 Aug	Avianca
04 Jul - 06 Jul	Avianca
02 Jul - 06 Jul	Avianca
03 Jul - 06 Jul	Avianca
02 Jul - 05 Jul	Avianca
26 Jul - 02 Aug	United	direct
17 Jul - 20 Jul	United	direct
03 Jul - 04 Aug	United	direct

Also check the deals for one-way flights from Houston to Panama City in July.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Panama City in July from $514

Return flights