AirHint found the following cheapest return flights from Houston (HOU) to Santiago (SCL) in October 2025 (see full year).
Return flights
| 12 Oct - 26 Nov | Spirit Airlines | ||
| 17 Oct - 27 Oct | Spirit Airlines | ||
| 04 Oct - 25 Oct | American Airlines |
Also check the deals for one-way flights from Houston to Santiago in October.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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