AirHint found the following cheapest return flights from Houston (IAH) to Guatemala City (GUA) in October 2025 (see full year).

Return flights

27 Oct - 10 Nov	Spirit Airlines
27 Oct - 05 Nov	Spirit Airlines
27 Oct - 30 Oct	Spirit Airlines
25 Oct - 05 Nov	Spirit Airlines
29 Oct - 05 Nov	Spirit Airlines
25 Oct - 30 Oct	Spirit Airlines
29 Oct - 30 Oct	Spirit Airlines
25 Oct - 10 Nov	Spirit Airlines
29 Oct - 10 Nov	Spirit Airlines
06 Oct - 20 Oct	United	direct
27 Oct - 10 Nov	United	direct
04 Oct - 18 Oct	United	direct
05 Oct - 19 Oct	United	direct
10 Oct - 24 Oct	United	direct
11 Oct - 25 Oct	United	direct
02 Oct - 16 Oct	United	direct

Also check the deals for one-way flights from Houston to Guatemala City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Guatemala City in October from $294

Return flights