AirHint found the following cheapest return flights from Iguazu Falls (IGR) to Santiago (SCL) in October 2025 (see full year).

Return flights

01 Oct - 04 Oct	JetSmart
01 Oct - 06 Oct	JetSmart
17 Oct - 06 Nov	JetSmart
16 Oct - 25 Oct	JetSmart
31 Oct - 06 Nov	JetSmart
17 Oct - 25 Oct	JetSmart
16 Oct - 02 Nov	JetSmart
01 Oct - 13 Oct	JetSmart
01 Oct - 05 Oct	JetSmart
16 Oct - 06 Nov	JetSmart
01 Oct - 18 Oct	JetSmart
14 Oct - 25 Oct	JetSmart
31 Oct - 02 Nov	JetSmart
25 Oct - 06 Nov	JetSmart
17 Oct - 02 Nov	JetSmart
16 Oct - 18 Oct	JetSmart
14 Oct - 02 Nov	JetSmart
31 Oct - 07 Nov	JetSmart
17 Oct - 18 Oct	JetSmart
25 Oct - 02 Nov	JetSmart

Also check the deals for one-way flights from Iguazu Falls to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Iguazu Falls to Santiago in October from $258

Return flights