Cheapest return flights from Indianapolis to Rome in October from $444

AirHint found the following cheapest return flights from Indianapolis (IND) to Rome (FCO) in October 2025 (see full year).

Return flights

21 Oct - 04 Nov Spirit Airlines
20 Oct - 04 Nov Spirit Airlines
18 Oct - 25 Oct Spirit Airlines
03 Oct - 13 Oct Spirit Airlines
31 Oct - 07 Nov United
21 Oct - 28 Oct United
16 Oct - 23 Oct United
26 Oct - 02 Nov United
01 Oct - 08 Oct United
06 Oct - 13 Oct United
11 Oct - 18 Oct United

Also check the deals for one-way flights from Indianapolis to Rome in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome

Feel free to contact us with any feedback or request another flight research.