AirHint found the following cheapest return flights from Islamabad (ISB) to Rome (FCO) in September 2025 (see full year).

Return flights

26 Sep - 02 Oct	Etihad Airways
10 Sep - 19 Sep	Serene Air
19 Sep - 24 Sep	flydubai
12 Sep - 19 Sep	SalamAir
10 Sep - 17 Sep	Serene Air
19 Sep - 22 Sep	flydubai
09 Sep - 16 Sep	Fly Jinnah
09 Sep - 19 Sep	Fly Jinnah
30 Sep - 08 Oct	Saudia
24 Sep - 30 Sep	Saudia
26 Sep - 03 Oct	Qatar Airways
30 Sep - 30 Sep	British Airways
23 Sep - 02 Oct	Emirates
20 Sep - 11 Oct	Qatar Airways

Also check the deals for one-way flights from Islamabad to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Islamabad to Rome in September from $594

Return flights