AirHint found the following cheapest return flights from Istanbul (IST) to Cape Town (CPT) in September 2025 (see full year).

Return flights

08 Sep - 15 Sep	Etihad Airways
01 Sep - 08 Sep	Etihad Airways
12 Sep - 19 Sep	Etihad Airways
06 Sep - 13 Sep	Etihad Airways
13 Sep - 21 Sep	Pegasus Airlines
11 Sep - 21 Sep	KLM
22 Sep - 28 Sep	KLM
19 Sep - 28 Sep	KLM
07 Sep - 11 Sep	KLM
03 Sep - 12 Sep	KLM
15 Sep - 05 Oct	Qatar Airways
27 Sep - 05 Oct	Turkish Airlines	direct
15 Sep - 05 Oct	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Cape Town in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Cape Town in September from $709

Return flights